calendar_today 06 Mar, 2027
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directions_run Running
language Official Website
sell $25.00
Please join us for the 12th Annual Race the Helix-Upstate, inspired by one family's desire to raise awareness for genetic disorders and funding for genetic research! All proceeds benefit the Greenwood Genetic Center Foundation to support genetics services, testing, and research for families impacted by genetic disorders.
Please see the information below regarding our live and virtual events!
| Date | Saturday, March 7, 2026 |
| Location | Lake Conestee Nature Park |
| Address | 840 Mauldin Rd, Greenville, SC 29607 |
| Check-In | Starts at 8:00 AM on the day of the race Parking is available at Lake Conestee Nature Park (840 Mauldin Rd, Greenville, SC 29607). Please arrive at least 30 minutes before your start to park and check in, follow any posted signs or volunteers, and carpool if you can. |
| 8:45 AM | Pre-race announcements and course briefing |
| 9:00 AM | Race the Helix 5K starts |
| 9:00 AM | Walk the Helix 1 mile starts |
| 9:55 AM | Awards (results are live on the race page as runners finish) |
| 10:15 AM | Course closes |
Times are based on the start times above.
The course map will be posted before race day.
All proceeds from Race the Helix-Upstate will benefit the Greenwood Genetic Center Foundation. For more information about the Greenwood Genetic Center Foundation or to make a donation, please visit the link below.
This race is one of the community charity races in the Upstate Giving Series, which connects local races with the Upstate nonprofits they support. Every finish counts toward the series standings.
Thank you to the businesses and partners who make this race possible.


Mar 06, 2027
Distance — 5K
Type — Running
09:00
$25.00
Mar 06, 2027
Distance — 5K
Type — Running
09:00
$25.00
Mar 06, 2027
Distance — 1.6K
Type — Running
09:00
$0.00
Mar 06, 2027
Distance — 1.6K
Type — Running
09:00
$0.00
These values represent the 3-year monthly averages for March in Greenville.
Learn more about the host city, Greenville.
Greenville has been described as Athens, Georgia for adults. It is the county seat and largest city of Greenville County, South Carolina, United States. Greenville is also the center of the largest metropolitan area of South Carolina. Columbia, Charleston, and North Charleston have more people, but the urban area around Greenville is larger. With its historic homes and modern office towers, Greenville is said to be where "Old South" meets "New South".
Read more launchTours and activities near Greenville, powered by Viator.
Watch highlights and course previews from previous years.
Read what other athletes have to say about their experience at the Race the Helix-Upstate.
Be the first to share your experience with the community!
Spotted an error or missing detail about the Race the Helix-Upstate? Help us improve.
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